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Description & Relevance


Big and complex data is fuelling diverse research directions in both medical image analysis and computer vision research fields. These can be divided into two main categories: (1) analytical methods, and (2) predictive methods. While analytical methods aim to efficiently analyse, represent and interpret data (static or longitudinal), predictive methods leverage the data currently available to predict observations at later time-points (i.e., forecasting the future) or predicting observations at earlier time-points (i.e., predicting the past for missing data completion). For instance, a method which only focuses on classifying patients with mild cognitive impairment (MCI) and patients with Alzheimer’s disease (AD) is an analytical method, while a method which predicts if a subject diagnosed with MCI will remain stable or convert to AD over time is a predictive method. Similar examples can be established for various neurodegenerative or neuropsychiatric disorders, degenerative arthritis or in cancer studies, in which the disease/disorder develops over time.

Why predictive intelligence?

It would constitute a stunning progress in the MICCAI research community if, in a few years, we contribute to engineering a ‘predictive intelligence’ which can map both low-dimensional and high-dimensional medical data onto the future with high precision. This workshop is the first endeavor to drive the field of ‘high-precision predictive medicine’, where late medical observations are predicted with high precision, while providing explanation via machine and deep learning, and statistically, mathematically- or physically-based models of healthy, disordered development and ageing. Despite the terrific progress that analytical methods have made in the last twenty years in medical image segmentation, registration or other related applications, efficient predictive intelligent models/methods are somewhat lagging behind. As such predictive intelligence develops and improves —and this is likely to do so exponentially in the coming years— this will have far-reaching consequences for the development of new treatment procedures and novel technologies. These predictive models will begin to shed light on one of the most complex healthcare and medical challenges we have ever encountered, and, in doing so, change our basic understanding of who we are.

What kind of research problems we aim to solve?

The main aim of PRIME-MICCAI is to propel the advent of predictive models in a broad sense, with application to medical data. Particularly, the workshop will admit 8-page papers describing new cutting-edge predictive models and methods that solve challenging problems in the medical field. We hope that PRIME workshop becomes a nest for high-precision predictive medicine, one that is set to transform multiple fields of healthcare technologies in unprecedented ways.

Topics of interests include but are not limited to predictive methods dedicated to the following topics:

  • Modeling and predicting disease development or evolution from a limited number of observations;
  • Computer-aided prognostic methods (e.g., for brain diseases, prostate cancer, cervical cancer, dementia, acute disease, neurodevelopmental disorders);
  • Forecasting disease/cancer progression over time;
  • Predicting low-dimensional data (e.g., behavioral scores, clinical outcome, age, gender);
  • Predicting the evolution or development of high-dimensional data (e.g., shapes, graphs, images, patches, abstract features, learned features);
  • Predicting high-resolution data from low-resolution data;
  • Prediction methods using 2D, 2D+t, 3D, 3D+t, ND and ND+t data;
  • Predicting image modality from a different modality (e.g., data synthesis);
  • Predicting lesion evolution;
  • Predicting missing data (e.g., data imputation or data completion problems).
  • Predicting clinical outcome from medical data (genomic, imaging data, etc).


This workshop will mediate ideas from both machine learning and mathematical/statistical/physical modeling research directions in the hope to provide a deeper understanding of the foundations of predictive intelligence developed for medicine, as well as to where we currently stand and what we aspire to achieve through this field. PRIME-MICCAI 2018 will feature a single-track workshop with keynote speakers with deep expertise in high-precision predictive medicine using machine learning and other modeling approaches —which are believed to stand at opposing directions. Our workshop will also include technical paper presentations, poster sessions, and demonstrations. Eventually, this will help steer a wide spectrum of MICCAI publications from being ‘only analytical’ to being ‘jointly analytical and predictive’.


Keynote Speakers

Short bio: Dinggang Shen is Jeffrey Houpt Distinguished Investigator, and a Professor of Radiology, Biomedical Research Imaging Center (BRIC), Computer Science, and Biomedical Engineering in the University of North Carolina at Chapel Hill (UNC-CH). He is currently directing the Center for Image Analysis and Informatics, the Image Display, Enhancement, and Analysis (IDEA) Lab in the Department of Radiology, and also the medical image analysis core in the BRIC. He was a tenure-track assistant professor in the University of Pennsylvanian (UPenn), and a faculty member in the Johns Hopkins University. Dr. Shen’s research interests include medical image analysis, computer vision, and pattern recognition. He has published more than 800 papers in the international journals and conference proceedings, with H-index 83. He serves as an editorial board member for eight international journals. He has also served in the Board of Directors, The Medical Image Computing and Computer Assisted Intervention (MICCAI) Society, in 2012-2015. He will be General Chair for MICCAI 2019. He is a Fellow of IEEE, Fellow of The American Institute for Medical and Biological Engineering (AIMBE), and Fellow of The International Association for Pattern Recognition (IAPR).

Short bio: Ender Konukoglu studied Electrical Engineering at Bogazici University, Turkey, and did a PhD on medical image analysis at INRIA Sophia Antipolis, France. He worked at Microsoft Research Cambridge as a post-doctoral researcher and at Athinoula A. Martinos Center / Harvard Medical School as junior faculty. In 2016, he joined ETH Zurich as an assistant professor of biomedical image computing. His research focuses on machine learning in medical imaging and biophysical models.

Short bio: Dr Ipek Oguz is an Assistant Professor in the Department of Electrical Engineering and Computer Science at Vanderbilt University. She received her Ph.D. in Computer Science at the University of North Carolina at Chapel Hill. Prior to joining Vanderbilt, she spent time in the Penn Image Computing and Science Laboratory (PICSL) and Center for Biomedical Image Computing and Analytics (CBICA) at the University of Pennsylvania as well as in the Iowa Institute for Biomedical Imaging (IIBI) at the University of Iowa. Her research is in the field of medical image analysis and specifically in the development of novel methodology for quantitative medical image analysis, with applications to neuroimaging, including Huntington’s disease and multiple sclerosis. Her technical interests include graph-based segmentation methods and longitudinal studies. She has co-authored more than 50 peer-reviewed journal and conference publications. She is an executive in the Women in MICCAI Committee and a co-chair of IPMI 2017.

Short bio: Kilian M. Pohl received the PhD degree from the Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology. He is currently the Program Director of Biomedical Computing at the Center for Health Sciences, SRI International. His research focuses  on creating algorithms  aimed at identifying biomedical phenotypes  accelerating the mechanistic understanding, diagnosis, and treatment of neuropsychiatric disorders.

Program Committee Members

Ahmed Fetit, Imperial College London, UK

Avinash Varadarajan, Google AI Healthcare, USA

Changqing Zhang, Tianjin University, China

Daniel Rueckert, Imperial College London, UK

Dong Nie, University of North Carolina (UNC), USA

Gang Li, University of North Carolina (UNC), USA

Gerard Sanroma, Pompeu Fabra University, Spain

Guorong Wu, University of North Carolina (UNC), USA

Hamid Soltanian-Zadeh, University of Tehran, Iran and Henry Ford Hospital, USA

Ilwoo Lyu, Vanderbilt University, USA

Jaeil Kim, Kyungpook National University (KNU), Korea

Jon Krause, Google AI Healthcare, USA

Le Lu, NVidia Corp, USA

Li Wang, University of North Carolina (UNC), USA

Marc Niethammer, University of North Carolina (UNC), USA

Mehdi Moradi, IBM Research, USA

Mert Sabuncu, Cornell University, USA

Morteza Mardani, Stanford University, USA

Polina Golland, Massachusetts Institute of Technology (MIT), USA

Qian Wang, Shanghai Jiao Tong University (SJTU), China

Qingyu Zhao, Stanford University, USA

Serena Yeung, Stanford University, USA

Stefanie Demirci, Technische Universität München (TUM), Germany

Tal Arbel, McGill University, Canada

Ulas Bagci, University of Central Florida (UCF), USA

Yinghuan Shi, Nanjing University, China

YingYing Zhu, Cornell University, USA

Yu Zhang, Stanford University, USA

Yue Gao, Tsinghua University, China

Ziga Spiclin, University of Ljubljana, Slovenia  


Papers are limited to eight pages, and formatted in Springer LNCS style. PRIME reviewing is double-blind.

For paper submission, please use the following link:

Key dates:

Full Paper Deadline: June 11, 2018; 11:59 PM PST; extended to June 25, 2018; 11:59 PM PST 

Notification of Acceptance: July 15, 2018

Camera-ready Version: July 20, 2018, 11:59 PM PST (Please download the Springer PRIME copyright form “PRIME_LNCS_2018 to fill out)

Workshop date: Sept 16, 2018

To download PRIME flyer click on PRIME-MICCAI_2018_flyer_final.

Instructions for submitting your camera-ready paper:

Please make sure to upload a zip file including the following documents:
1. The final camera-ready PDF of your paper.
2. All original files required to generate the final PDF. If you are using Latex, please make sure to include .tex, .bib, figures, and any other files for compiling the tex file. If you are using Word, please upload the docx file.
3. Please fill out the Springer copyright form which can be found using this link:
Please make sure that the copyright forms have been filled out correctly before uploading the zip file.

PRIME-MICCAI 2018 proceedings will be published in Springer’s LNCS (Lecture Notes in Computer Science),

Many thanks.

Our upcoming special Issue:

The accepted papers can be further extended and submitted to our upcoming special issue (SI) in IEEE Journal of Biomedical and Health Informatics. We note that if the submitted paper to the SI are extensions of conference papers, we request that each paper has at least 70% new material compared to the conference papers.

Best PRIME-MICCAI Paper Award:

is our ‘Best Paper Award’ Sponsor. 


To access the tentative program for PRIME-MICCAI 2018, please click on: PRIME-MICCAI 2018 Program Updated



You can access the PRIMe MICCAI LNCS proceedings via this link:​